Feasibility of free-breathing quantitative myocardial perfusion using multi-echo Dixon magnetic resonance imaging.

ABSTRACT: Dynamic contrast-enhanced quantitative first-pass perfusion using magnetic resonance imaging enables non-invasive objective assessment of myocardial ischemia without ionizing radiation. However, quantification of perfusion is challenging due to the non-linearity between the magnetic resonance signal intensity and contrast agent concentration. Furthermore, respiratory motion during data acquisition precludes quantification of perfusion. While motion correction techniques have been proposed, they have been hampered by the challenge of accounting for dramatic contrast changes during the bolus and long execution times. In this work we investigate the use of a novel free-breathing multi-echo Dixon technique for quantitative myocardial perfusion. The Dixon fat images, unaffected by the dynamic c

SUBMITTER: Scannell CM 

PROVIDER: S-EPMC7392760 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature