Nasal decolonization of Staphylococcus aureus and the risk of surgical site infection after surgery: a meta-analysis.

ABSTRACT:

Aim

To assess the effects of nasal decontamination on preventing surgical site infections (SSIs) in people who are Staphylococcus aureus carriers undergoing different types of surgeries and diverse measures of decolonization.

Methods

Relevant randomized controlled trials (RCTs) were identified through systematic searches of the PubMed, Embase, Web of science, and the Cochrane Library databases. The risk ratios (RRs) and 95% confidence intervals (CIs) were calculated and the effects model was chosen according to the heterogeneity. Subgroup analyses were performed according to different types of surgeries and measures of decolonization that Staphylococcus aureus carriers were applied.

Results

Twenty RCTs published between 1996 and 2019 involving 10,526 patients were inc

SUBMITTER: Tang J 

PROVIDER: S-EPMC7392830 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature