Newborn white matter microstructure moderates the association between maternal postpartum depressive symptoms and infant negative reactivity.

ABSTRACT: Maternal postpartum depression is a prominent risk factor for aberrant child socioemotional development, but there is little understanding about the neural phenotypes that underlie infant sensitivity to maternal depression. We examined whether newborn white matter fractional anisotropy (FA), a measure of white matter maturity, moderates the association between maternal postpartum depressive symptoms and infant negative reactivity at 6 months. Participants were 80 mother-infant dyads participating in a prospective population-based cohort, and included families whose newborns underwent a magnetic resonance/diffusion tensor imaging scan at 2-5 weeks of age and whose mothers reported their own depressive symptoms at 3 and 6 months postpartum and infant negative emotional reactivity at 6 months

SUBMITTER: Nolvi S 

PROVIDER: S-EPMC7393309 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature