Common and distinct functional stability abnormalities across three major psychiatric disorders.

ABSTRACT: Delineating the neuropathological characteristics across psychiatric disorders is critical for understanding their pathophysiology. The purpose of this study was to investigate common and distinct brain functional abnormalities across psychiatric disorders by using functional stability, a recently developed dynamic functional connectivity approach. Resting-state functional magnetic resonance imaging data were collected from a transdisease sample of healthy controls (n = 115) and individuals with schizophrenia (SZ) (n = 47), bipolar disorder (BD) (n = 44), and attention deficit/hyperactivity disorder (ADHD) (n = 40). Functional stability of each voxel was calculated by measuring the concordance of dynamic functional connectivity over time. Differences in functional stability among the four

SUBMITTER: Zhu J 

PROVIDER: S-EPMC7393318 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature