Development and validation of a novel scoring system developed from a nomogram to identify malignant pleural effusion.

ABSTRACT:

Background

This study aimed to establish and validate a novel scoring system based on a nomogram for the differential diagnosis of malignant pleural effusion (MPE) and benign pleural effusion (BPE).

Methods

Patients with PE and confirmed aetiology who underwent diagnostic thoracentesis were included in this study. One retrospective set (N = 1261) was used to develop and internally validate the predictive model. The clinical, radiological and laboratory features were collected and subjected to logistic regression analyses. The primary predictive model was displayed as a nomogram and then modified into a novel scoring system, which was externally validated in an independent set (N = 172).

Findings

The novel scoring system was composed of fever (3 points), erythrocyte se

SUBMITTER: Wang S 

PROVIDER: S-EPMC7393523 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature