Dissociations in cortical thickness and surface area in non-comorbid never-treated patients with social anxiety disorder.

ABSTRACT:

Background

Abnormalities of functional activation and cortical volume in brain regions involved in the neurobiology of fear and anxiety have been implicated in the pathophysiology of social anxiety disorder (SAD). However, few studies have performed separate measurements of cortical thickness (CT) and cortical surface area (CSA) which reflect different neurobiological processes. Thus, we aimed to explore the cortical morphological anomaly separately in SAD using FreeSurfer.

Methods

High-resolution structural magnetic resonance images were obtained from 32 non-comorbid never-treated adult SAD patients and 32 demography-matched healthy controls. Cortical morphometry indices including CT and CSA were separately determined by FreeSurfer and compared between the two groups via wh

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7393569 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature