In silico Functional Annotation and Characterization of Hypothetical Proteins from Serratia marcescens FGI94.

ABSTRACT: Serratia marcescens, rod-shaped Gram-negative bacteria is classified as an opportunistic pathogen in the family Enterobacteriaceae. It causes a wide variety of infections in humans, including urinary, respiratory, ocular lens and ear infections, osteomyelitis, endocarditis, meningitis and septicemia. Unfortunately, over the past decade, antibiotic resistance has become a serious health care issue; the effective means to control and dissemination of S. marcescens resistance is the need of hour. The whole genome sequencing of S. marcescens FGI94 strain contains 4434 functional proteins, among which 690 (15.56%) proteins were classified under hypothetical. In the present study, we applied the power of various bioinformatics tools on the basis of protein family comparison,

SUBMITTER: Prabhu D 

PROVIDER: S-EPMC7394047 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature