Multifractal and Entropy-Based Analysis of Delta Band Neural Activity Reveals Altered Functional Connectivity Dynamics in Schizophrenia.

ABSTRACT: Dynamic functional connectivity (DFC) was established in the past decade as a potent approach to reveal non-trivial, time-varying properties of neural interactions - such as their multifractality or information content -, that otherwise remain hidden from conventional static methods. Several neuropsychiatric disorders were shown to be associated with altered DFC, with schizophrenia (SZ) being one of the most intensely studied among such conditions. Here we analyzed resting-state electroencephalography recordings of 14 SZ patients and 14 age- and gender-matched healthy controls (HC). We reconstructed dynamic functional networks from delta band (0.5-4 Hz) neural activity and captured their spatiotemporal dynamics in various global network topological measures. The acquired network measure ti

SUBMITTER: Racz FS 

PROVIDER: S-EPMC7394222 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature