Zinc for the prevention and treatment of SARS-CoV-2 and other acute viral respiratory infections: a rapid review.

ABSTRACT:

Background

The global COVID-19 pandemic has prompted an urgent search for interventions to prevent and treat SARS-CoV-2. Higher risk of infection and adverse outcomes coincide with populations with chronic diseases and elderly who are at risk of zinc deficiency. Through several mechanisms zinc may prevent, reduce severity and duration of symptoms.

Method

An a priori protocol was registered with PROSPERO on 27th April 2020 (CRD42020182044). Eight databases (one Chinese) and four clinical trial registries (one Chinese) were searched for randomised and quasi-randomised controlled trials (RCTs), evaluating single or adjunct zinc against placebo or active controls, for prevention and/or treatment of SARS-CoV-2, other coronaviruses or related infections. RR constraints incl

SUBMITTER: Arentz S 

PROVIDER: S-EPMC7395818 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature