Cardiovascular autonomic reflex function after bilateral cardiac sympathetic denervation for ventricular arrhythmias.

ABSTRACT:

Background

Bilateral cardiac sympathetic denervation (BCSD) is an effective therapy for ventricular arrhythmias (VAs) in cardiomyopathies (CMPs). After BCSD, residual autonomic nervous system (ANS) function is unknown.

Objective

The purpose of this study was to assess ANS responses in patients with CMP before and after BCSD as compared with demographically matched healthy controls.

Methods

Patients with CMP undergoing BCSD and matched healthy controls were recruited. Noninvasive measures-finger cuff beat-to-beat blood pressure (BP), electrocardiography, palmar electrodermal activity (EDA), and finger pulse volume (FPV)-were obtained at rest and during autonomic stressors-posture change, handgrip, and mental stress. Maximal as well as specific responses to stressors we

SUBMITTER: Dusi V 

PROVIDER: S-EPMC7395890 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature