Safety Profile of Slit-Lamp-Delivered Retinal Laser Photobiomodulation.

ABSTRACT:

Purpose

Photobiomodulation (PBM) refers to therapeutic irradiation of tissue with low-energy, 630- to 1000-nm wavelength light. An increasing body of evidence supports a beneficial effect of PBM in retinal disorders. To date, most studies have utilized light-emitting diode irradiation sources. Slit-lamp-mounted retinal lasers produce a coherent beam that can be delivered with precisely defined dosages and predetermined target area; however, the use of retinal lasers raises safety concerns that warrant investigation prior to clinical application. In this study, we determined safe dosages of laser-delivered PBM to the retina.

Methods

A custom-designed, slit-lamp-delivered, 670-nm, red/near-infrared laser was used to administer a range of irradiances to healthy pigmented and no

SUBMITTER: Ao J 

PROVIDER: S-EPMC7396177 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature