Hidradenitis suppurativa and psychiatric comorbidities, suicides and substance abuse: systematic review and meta-analysis.

ABSTRACT:

Background

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder of the hair follicles, and has been associated with a multitude of systemic disorders and pathologies. There is increasing evidence to suggest that chronic inflammatory skin disorders may be associated with psychiatric comorbidities, however this relationship has not been well established. We aimed perform a systematic review and meta-analysis to assess the association between HS and psychiatric comorbidities, suicide and substance abuse.

Methods

A systematic review and meta-analysis was performed according to PRISMA guidelines.

Results

HS cases had a significantly higher odds of having schizophrenia compared to the control group (OR 1.66, 95% CI: 1.53-1.79, P<0.00001). There was also a s

SUBMITTER: Phan K 

PROVIDER: S-EPMC7396254 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature