A consideration of publication-derived immune-related associations in Coronavirus and related lung damaging diseases.

ABSTRACT:

Background

The severe acute respiratory syndrome virus SARS-CoV-2, a close relative of the SARS-CoV virus, is the cause of the recent COVID-19 pandemic affecting, to date, over 14 million individuals across the globe and demonstrating relatively high rates of infection and mortality. A third virus, the H5N1, responsible for avian influenza, has caused infection with some clinical similarities to those in COVID-19 infections. Cytokines, small proteins that modulate immune responses, have been directly implicated in some of the severe responses seen in COVID-19 patients, e.g. cytokine storms. Understanding the immune processes related to COVID-19, and other similar infections, could help identify diagnostic markers and therapeutic targets.

Methods

Here we examine data of cytok

SUBMITTER: Geifman N 

PROVIDER: S-EPMC7397454 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature