Twenty-year sociodemographic trends in lung cancer in non-smokers: A UK-based cohort study of 3.7 million people.

ABSTRACT:

Introduction

There are reports that lung cancer in non-smokers (LCINS) is increasing in the United Kingdom (UK) and other high-income countries but evidence from large-scale cohort studies to support this claim is limited.

Material and methods

Using The Health Improvement Network (THIN) IQVIA™ Medical Research Data, we identified a cohort of 3,679,831 people from the UK self-reporting to their primary care physician as never or non-smokers. We estimated age-adjusted incidence rates for recorded lung cancer before (1998-2007) and after (2008-2018) the introduction of smoke-free legislation using multivariable Poisson regression. We also explored the impact of geographic location, social deprivation and urbanicity.

Results

The analysis included 3,212 lung cancer events

SUBMITTER: Rait G 

PROVIDER: S-EPMC7397470 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature