What Type of Prostate Cancer Is Systematically Overlooked by Multiparametric Magnetic Resonance Imaging? An Analysis from the PROMIS Cohort.

ABSTRACT:

Background

All risk stratification strategies in cancer overlook a spectrum of disease. The Prostate MR Imaging Study (PROMIS) provides a unique opportunity to explore cancers that are overlooked by multiparametric magnetic resonance imaging (mpMRI).

Objective

To summarise attributes of cancers that are systematically overlooked by mpMRI.

Design, setting, and participants

PROMIS tested performance of mpMRI and transrectal ultrasonography (TRUS)-guided biopsy, using 5 mm template mapping (TPM) biopsy as the reference standard.

Outcome measurements and statistical analysis

Outcomes were overall and maximum Gleason scores, maximum cancer core length (MCCL), and prostate-specific antigen density (PSAD). Cancer attributes were compared between cancers that were over

SUBMITTER: Norris JM 

PROVIDER: S-EPMC7397509 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature