The eye, the kidney, and cardiovascular disease: old concepts, better tools, and new horizons.

ABSTRACT: Chronic kidney disease (CKD) is common, with hypertension and diabetes mellitus acting as major risk factors for its development. Cardiovascular disease is the leading cause of death worldwide and the most frequent end point of CKD. There is an urgent need for more precise methods to identify patients at risk of CKD and cardiovascular disease. Alterations in microvascular structure and function contribute to the development of hypertension, diabetes, CKD, and their associated cardiovascular disease. Homology between the eye and the kidney suggests that noninvasive imaging of the retinal vessels can detect these microvascular alterations to improve targeting of at-risk patients. Retinal vessel-derived metrics predict incident hypertension, diabetes, CKD, and cardiovascular disease and add t

SUBMITTER: Farrah TE 

PROVIDER: S-EPMC7397518 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature