Genetic evidence for imported malaria and local transmission in Richard Toll, Senegal.

ABSTRACT:

Background

Malaria elimination efforts can be undermined by imported malaria infections. Imported infections are classified based on travel history.

Methods

A genetic strategy was applied to better understand the contribution of imported infections and to test for local transmission in the very low prevalence region of Richard Toll, Senegal.

Results

Genetic relatedness analysis, based upon molecular barcode genotyping data derived from diagnostic material, provided evidence for both imported infections and ongoing local transmission in Richard Toll. Evidence for imported malaria included finding that a large proportion of Richard Toll parasites were genetically related to parasites from Thiès, Senegal, a region of moderate transmission with extensive available genotyp

SUBMITTER: Daniels RF 

PROVIDER: S-EPMC7397603 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature