Changing relative risk of clinical factors for hospital-acquired acute kidney injury across age groups: a retrospective cohort study.

ABSTRACT:

Background

Likelihood of developing acute kidney injury (AKI) increases with age. We aimed to explore whether the predictability of AKI varies between age groups and assess the volatility of risk factors using electronic medical records (EMR).

Methods

We constructed a retrospective cohort of adult patients from all inpatient units of a tertiary care academic hospital and stratified it into four age groups: 18-35, 36-55, 56-65, and > 65. Potential risk factors collected from EMR for the study cohort included demographics, vital signs, medications, laboratory values, past medical diagnoses, and admission diagnoses. AKI was defined based on the Kidney Disease Improving Global Outcomes (KDIGO) serum creatinine criteria. We analyzed relative importance of the risk factors in pred

SUBMITTER: Wu L 

PROVIDER: S-EPMC7397647 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature