Marburg virus disease: A summary for clinicians.

ABSTRACT:

Objectives

This article summarizes the countermeasures for Marburg virus disease, focusing on pathogenesis, clinical features and diagnostics. There is an emphasis on therapies and vaccines that have demonstrated, through their evaluation in nonhuman primates (NHPs) and/or in humans, potential for use in an emergency situation.

Methods

A standardized literature review was conducted on vaccines and treatments for Marburg virus disease, with a focus on human and nonhuman primate data published in the last five years. More detail on the methods that were used is summarized in a companion methods paper.

Results

The study identified six treatments and four vaccine platforms that have demonstrated, through their efficacy in NHPs, potential benefit for treating or preventing

SUBMITTER: Kortepeter MG 

PROVIDER: S-EPMC7397931 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature