Higher toenail selenium is associated with increased insulin resistance risk in omnivores, but not in vegetarians.

ABSTRACT:

Background

The relationship between selenium (Se) and insulin resistance remains unclear. We aim to explore the association between toenail Se levels and insulin resistance through a cross-sectional study comprising Chinese vegetarians and matched omnivores.

Methods

In this study, we enrolled 220 vegetarians and 220 omnivores matched by age and sex from Shanghai. The inductively coupled plasma mass spectrometry method was used to measure toenail Se levels. Dietary Se intakes were assessed by the 24-h dietary recall method. Blood samples were collected to measure fasting blood glucose level and fasting insulin concentrations. Insulin resistance index (HOMA-IR) and insulin secretion index (HOMA-B) were calculated to evaluate insulin resistance. Multi-linear regression analysis

SUBMITTER: Gu Q 

PROVIDER: S-EPMC7398369 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature