Combining node location and node ratio as a prognostic factor for surgical resected non-small cell lung cancer: a population-based study.

ABSTRACT:

Background

In the TNM system only the anatomic location is used to define nodal status. In this study we aim to evaluate the effectiveness of combining the location and ratio of metastatic lymph node (pN-NR) for the prognosis of non-small cell lung cancer (NSCLC).

Methods

Patients with pN1/pN2 NSCLC were retrieved from the SEER database. The optimal cut point of NR was determined with the maximal selecting test. All patients were divided into 4 categories with combination of pN (pN1 or pN2) and NR (low or high). The pN-NR was investigated as a predictor of overall survival (OS) and cause-specific survival (CSS) using Cox regression models. Survival curves were plotted using the Kaplan-Meier method and the difference was compared with log-rank test.

Results

A total of

SUBMITTER: Xing H 

PROVIDER: S-EPMC7399421 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature