Freeze-all versus fresh blastocyst transfer strategy during in vitro fertilisation in women with regular menstrual cycles: multicentre randomised controlled trial.

ABSTRACT:

Objective

To compare the ongoing pregnancy rate between a freeze-all strategy and a fresh transfer strategy in assisted reproductive technology treatment.

Design

Multicentre, randomised controlled superiority trial.

Setting

Outpatient fertility clinics at eight public hospitals in Denmark, Sweden, and Spain.

Participants

460 women aged 18-39 years with regular menstrual cycles starting their first, second, or third treatment cycle of in vitro fertilisation or intracytoplasmic sperm injection.

Interventions

Women were randomised at baseline on cycle day 2 or 3 to one of two treatment groups: the freeze-all group (elective freezing of all embryos) who received gonadotropin releasing hormone agonist triggering and single frozen-thawed blastocyst transfer in

SUBMITTER: Stormlund S 

PROVIDER: S-EPMC7399608 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature