Investigating the potential antiviral activity drugs against SARS-CoV-2 by molecular docking simulation.

ABSTRACT: Recently, scary viral pneumonia is known as (COVID-19) has swept the whole world. The new virus strain designated as SARS-CoV-2 belonging to the coronavirus family. Although the current medical research directed towards the development of a novel therapeutic agent, no anti-viral drug approved until now. On the medical scale, the development of an approved drug is a time-consuming process, so research is directed towards screening of ligands and drugs multimodal structure-based-design and then docked to the main viral protease to investigate the active binding sites. The bioinformatic approaches used to evaluate the competence of a comprehensive range of ligands and drugs before their clinical implementation. In this study, a computational approach through molecular docking simulation is co

SUBMITTER: El-Hoshoudy AN 

PROVIDER: S-EPMC7399655 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature