Prevalence of High-risk Plaques and Risk of Stroke in Patients With Asymptomatic Carotid Stenosis: A Meta-analysis.

ABSTRACT:

Importance

There is an ongoing debate regarding the management of asymptomatic carotid stenosis. Previous studies have reported imaging features of high-risk plaques that could help to optimize the risk-benefit ratio of revascularization. However, such studies have not provided an accurate estimate of the prevalence of high-risk plaques and the associated annual incidence of ipsilateral ischemic cerebrovascular events to inform the design of clinical trials using a risk-oriented selection of patients before randomization.

Objective

To assess the relevance and feasibility of risk-oriented selection of patients for revascularization.

Data sources

A systematic search of PubMed and Ovid Embase from database inception to July 31, 2019, was performed.

Study selection

SUBMITTER: Kamtchum-Tatuene J 

PROVIDER: S-EPMC7400201 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature