Current Trends of Essential Trace Elements in Patients with Chronic Liver Diseases.

ABSTRACT: Essential trace elements play crucial roles in the maintenance of health, since they are involved in many metabolic pathways. A deficiency or an excess of some trace elements, including zinc, selenium, iron, and copper, frequently causes these metabolic disorders such as impaired glucose tolerance and dyslipidemia. The liver largely regulates most of the metabolism of trace elements, and accordingly, an impairment of liver functions can result in numerous metabolic disorders. The administration or depletion of these trace elements can improve such metabolic disorders and liver dysfunction. Recent advances in molecular biological techniques have helped to elucidate the putative mechanisms by which liver disorders evoke metabolic abnormalities that are due to deficiencies or excesses of thes

SUBMITTER: Himoto T 

PROVIDER: S-EPMC7400835 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature