O’Donoghue Sports Injury Award: Bridge-Enhanced ACL Repair is Non-Inferior to Autograft ACL Reconstruction at 2-Years: Results of a Prospective Randomized Clinical Trial

ABSTRACT:

Objectives:

Preclinical studies and an early clinical cohort study have suggested that for complete midsubstance ACL injuries, the technique of suture repair of the anterior cruciate ligament (ACL) augmented with a protein implant placed in the gap between the torn ends (bridge-enhanced ACL repair) may be a viable alternative to ACL reconstruction. We hypothesized that patients treated with bridge-enhanced ACL repair would have non-inferior patient reported outcomes and anteroposterior (AP) laxity, and superior hamstring strength at 2 years after surgery when compared with subjects who had ACL reconstruction with autograft.

Study Design:

Prospective Randomized Control Trial (NCT02664545).

Methods:

One hundred patients, ages 13 to 35, with complete mid-substance A

SUBMITTER:  

PROVIDER: S-EPMC7401061 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature