Noninvasive and Noncontact Sequential Imaging of the Iridocorneal Angle and the Cornea of the Eye.

ABSTRACT:

Purpose

High-resolution imaging of the critical anatomic structures of the eye, especially of the anterior chamber, in vivo, remains a challenge, even with currently available state-of-the-art medical imaging techniques. This study aims for the noninvasive and noncontact sequential imaging of the iridocorneal angle, especially the trabecular meshwork (TM) and the cornea of the eye in high-resolution using a newly developed imaging platform.

Methods

Bessel beam scanned light sheet fluorescence microscopy is used to attain high-resolution images of the TM. The ability of the Bessel beam to self-reconstruct around obstacles increases the image contrast at the TM region inside eye by reducing scattering and shadow artifacts. With minimal modifications, the excitation arm of the

SUBMITTER: Hong XJJ 

PROVIDER: S-EPMC7401920 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature