Dataset Information

Echo planar time-resolved imaging with subspace reconstruction and optimized spatiotemporal encoding.

ABSTRACT:

Purpose

To develop new encoding and reconstruction techniques for fast multi-contrast/quantitative imaging.

Methods

The recently proposed Echo Planar Time-resolved Imaging (EPTI) technique can achieve fast distortion- and blurring-free multi-contrast/quantitative imaging. In this work, a subspace reconstruction framework is developed to improve the reconstruction accuracy of EPTI at high encoding accelerations. The number of unknowns in the reconstruction is significantly reduced by modeling the temporal signal evolutions using low-rank subspace. As part of the proposed reconstruction approach, a B₀ -update algorithm and a shot-to-shot B₀ variation correction method are developed to enable the reconstruction of high-resolution tissue phase images and to mitigate artifacts from shot-to-shot phase variations. Moreover, the EPTI concept is extended to 3D k-space for 3D GE-EPTI, where a new "temporal-variant" of CAIPI encoding is proposed to further improve performance.

Results

The effectiveness of the proposed subspace reconstruction was demonstrated first in 2D GESE EPTI, where the reconstruction achieved higher accuracy when compared to conventional B₀ -informed GRAPPA. For 3D GE-EPTI, a retrospective undersampling experiment demonstrates that the new temporal-variant CAIPI encoding can achieve up to 72× acceleration with close to 2× reduction in reconstruction error when compared to conventional spatiotemporal-CAIPI encoding. In a prospective undersampling experiment, high-quality whole-brain T2∗ and tissue phase maps at 1 mm isotropic resolution were acquired in 52 seconds at 3T using 3D GE-EPTI with temporal-variant CAIPI encoding.

Conclusion

The proposed subspace reconstruction and optimized temporal-variant CAIPI encoding can further improve the performance of EPTI for fast quantitative mapping.

SUBMITTER: Dong Z

PROVIDER: S-EPMC7402016 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Publications

Echo planar time-resolved imaging with subspace reconstruction and optimized spatiotemporal encoding.

Dong Zijing Z Wang Fuyixue F Reese Timothy G TG Bilgic Berkin B Setsompop Kawin K

Magnetic resonance in medicine 20200425 5

<h4>Purpose</h4>To develop new encoding and reconstruction techniques for fast multi-contrast/quantitative imaging.<h4>Methods</h4>The recently proposed Echo Planar Time-resolved Imaging (EPTI) technique can achieve fast distortion- and blurring-free multi-contrast/quantitative imaging. In this work, a subspace reconstruction framework is developed to improve the reconstruction accuracy of EPTI at high encoding accelerations. The number of unknowns in the reconstruction is significantly reduced ...[more]

PMID: 32333478

Similar Datasets

Project description:PurposeTo develop EPTI, a multi-shot distortion-free multi-echo imaging technique, into a single-shot acquisition to achieve improved robustness to motion and physiological noise, increased temporal resolution, and high SNR efficiency for dynamic imaging applications.MethodsA new spatiotemporal encoding was developed to achieve single-shot EPTI by enhancing spatiotemporal correlation in k-t space. The proposed single-shot encoding improves reconstruction conditioning and sampling efficiency, with additional optimization under various accelerations to achieve optimized performance. To achieve high SNR efficiency, continuous readout with minimized deadtime was employed that begins immediately after excitation and extends for an SNR-optimized length. Moreover, k-t partial Fourier and simultaneous multi-slice acquisition were integrated to further accelerate the acquisition and achieve high spatial and temporal resolution.ResultsWe demonstrated that ss-EPTI achieves higher tSNR efficiency than multi-shot EPTI, and provides distortion-free imaging with densely-sampled multi-echo images at resolutions ~1.25-3 mm at 3T and 7T-with high SNR efficiency and with comparable temporal resolutions to ss-EPI. The ability of ss-EPTI to eliminate dynamic distortions common in EPI also further improves temporal stability. For fMRI, ss-EPTI also provides early-TE images (e.g., 2.9ms) to recover signal-intensity and functional-sensitivity dropout in challenging regions. The multi-echo images provide TE-dependent information about functional fluctuations, successfully distinguishing noise-components from BOLD signals and further improving tSNR. For diffusion MRI, ss-EPTI provides high-quality distortion-free diffusion images and multi-echo diffusion metrics.Conclusionss-EPTI provides distortion-free imaging with high image quality, rich multi-echo information, and enhanced efficiency within comparable temporal resolution to ss-EPI, offering a robust and efficient acquisition for dynamic imaging.

Project description:PurposeTo develop a single-shot SNR-efficient distortion-free multi-echo imaging technique for dynamic imaging applications.MethodsEcho planar time-resolved imaging (EPTI) was first introduced as a multi-shot technique for distortion-free multi-echo imaging. This work aims to develop single-shot EPTI (ss-EPTI) to achieve improved robustness to motion/physiological noise, increased temporal resolution, and higher SNR efficiency. A new spatiotemporal encoding that enables reduced phase-encoding blips and minimized echo spacing under the single-shot regime was developed, which improves sampling efficiency and enhances spatiotemporal correlation in the k-TE space for improved reconstruction. A continuous readout with minimized deadtime was employed to optimize SNR efficiency. Moreover, k-TE partial Fourier and simultaneous multi-slice acquisition were integrated for further acceleration.Resultsss-EPTI provided distortion-free imaging with densely sampled multi-echo images at standard resolutions (e.g., ˜1.25 to 3 mm) in a single-shot. Improved SNR efficiency was observed in ss-EPTI due to improved motion/physiological-noise robustness and efficient continuous readout. Its ability to eliminate dynamic distortions-geometric changes across dynamics due to field changes induced by physiological variations or eddy currents-further improved the data's temporal stability. For multi-echo fMRI, ss-EPTI's multi-echo images recovered signal dropout in short- T2*$$ {\mathrm{T}}_2^{\ast } $$ regions and provided TE-dependent functional information to distinguish non-BOLD noise for further tSNR improvement. For diffusion MRI, it achieved shortened TEs for improved SNR and provided images free from both B0-induced and diffusion-encoding-dependent eddy-current-induced distortions with multi-TE diffusion metrics.Conclusionss-EPTI provides SNR-efficient distortion-free multi-echo imaging with comparable temporal resolutions to ss-EPI, offering a new acquisition tool for dynamic imaging.

Dataset Information

Echo planar time-resolved imaging with subspace reconstruction and optimized spatiotemporal encoding.

Purpose

Methods

Results

Conclusion

Publications

Echo planar time-resolved imaging with subspace reconstruction and optimized spatiotemporal encoding.

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