Household transmission of SARS-CoV-2: a systematic review and meta-analysis of secondary attack rate.

ABSTRACT:

Background

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spread by direct, indirect, or close contact with infected people via infected respiratory droplets or saliva. Crowded indoor environments with sustained close contact and conversations are a particularly high-risk setting.

Methods

We performed a meta-analysis through July 29, 2020 of SARS-CoV-2 household secondary attack rate (SAR), disaggregating by several covariates (contact type, symptom status, adult/child contacts, contact sex, relationship to index case, index case sex, number of contacts in household, coronavirus).

Findings

We identified 40 relevant published studies that report household secondary transmission. The estimated overall household SAR was 18.8% (95% confidence interval [CI

SUBMITTER: Madewell ZJ 

PROVIDER: S-EPMC7402051 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature