Prevalence trends in non-alcoholic fatty liver disease at the global, regional and national levels, 1990-2017: a population-based observational study.

ABSTRACT:

Objective

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of end-stage liver diseases worldwide. Understanding NAFLD prevalence and trends over time at the global, regional and national levels is critical to understanding the NAFLD disease burden and creating more tailored prevention strategies.

Design

Population-based observational study.

Setting

The study was global, including 21 regions and 195 countries or territories.

Main outcomes measure

The estimated annual percentage change for NAFLD prevalence.

Results

Worldwide, cases of NAFLD have increased from 391.2 million in 1990 to 882.1 million in 2017, with the prevalence rate increasing from 8.2% to 10.9% during the same period. The increasing trends were consistent across sexes. Case n

SUBMITTER: Ge X 

PROVIDER: S-EPMC7402189 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature