Cartilage Homeostasis Affects Femoral Head Necrosis Induced by Methylprednisolone in Broilers.

ABSTRACT: (1) Background: Since the large-scale poultry industry has been established, femoral head necrosis (FHN) has always been a major leg disease in fast-growing broilers worldwide. Previous research suggested that cartilage homeostasis could be taken into consideration in the cause of FHN, but the evidence is insufficient. (2) Methods: One-day-old broiler chickens were randomly divided into three groups, 16 broilers per group. The birds in group L were injected intramuscularly with methylprednisolone (MP) twice a week for four weeks (12.5 mg·kg^-1). The birds in group H were injected intramuscularly with MP (20 mg·kg^-1·d^-1) for 7 d (impulse treatment). The birds in group C were treated with sterile saline as a control group. Broilers were sacrificed at 42 and 56

SUBMITTER: Yu Y 

PROVIDER: S-EPMC7402315 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature