SQUAT: a Sequencing Quality Assessment Tool for data quality assessments of genome assemblies.

ABSTRACT:

Background

With the rapid increase in genome sequencing projects for non-model organisms, numerous genome assemblies are currently in progress or available as drafts, but not made available as satisfactory, usable genomes. Data quality assessment of genome assemblies is gaining importance not only for people who perform the assembly/re-assembly processes, but also for those who attempt to use assemblies as maps in downstream analyses. Recent studies of the quality control, quality evaluation/ assessment of genome assemblies have focused on either quality control of reads before assemblies or evaluation of the assemblies with respect to their contiguity and correctness. However, correctness assessment depends on a reference and is not applicable for de novo assembly projects. Hence,

SUBMITTER: Yang LA 

PROVIDER: S-EPMC7402383 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature