CALIPER Hematology Reference Standards (II).

ABSTRACT:

Objectives

The objective of this study was to establish comprehensive age- and sex-specific reference intervals for hematologic parameters in the CALIPER cohort of healthy children and adolescents.

Methods

A total of 536 healthy children and adolescents (birth to 21 years) were recruited with informed consent, and whole blood samples were analyzed for 27 hematologic parameters on the Beckman Coulter DxH 520 system. Age- and sex-specific pediatric reference standards were established. Reference values obtained on the DxH 520 were also compared with data obtained on a larger laboratory-based instrument (DxH 900).

Results

Most hematologic parameters showed significant age- and/or sex-specific changes during growth and development. Of the 27 hematologic parameters, all ex

SUBMITTER: Higgins V 

PROVIDER: S-EPMC7403758 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature