CALIPER Hematology Reference Standards (I).

ABSTRACT:

Objectives

Accurate hematologic test interpretation based on normative reference standards is critical to ensure appropriate clinical decision making. However, healthy pediatric reference data for most hematology parameters are lacking. To address this gap, this study establishes age- and sex-specific hematologic reference standards in the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) cohort of healthy children and adolescents.

Methods

Fresh whole blood samples collected from a total of 566 healthy children and adolescents (birth to <21 years) with informed consent were analyzed for 47 hematologic parameters on the Beckman Coulter DxH 900. Age- and sex-specific reference standards were calculated based on the Clinical and Laboratory Standards Inst

SUBMITTER: Tahmasebi H 

PROVIDER: S-EPMC7403759 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature