Characteristics of Biopeptides Released In Silico from Collagens Using Quantitative Parameters.

ABSTRACT: The potential of collagens to release biopeptides was evaluated using the BIOPEP-UWM-implemented quantitative criteria including the frequency of the release of fragments with a given activity by selected enzyme(s) (A_E), relative frequency of release of fragments with a given activity by selected enzyme(s) (W), and the theoretical degree of hydrolysis (DH_t). Cow, pig, sheep, chicken, duck, horse, salmon, rainbow trout, goat, rabbit, and turkey collagens were theoretically hydrolyzed using: stem bromelain, ficin, papain, pepsin, trypsin, chymotrypsin, pepsin+trypsin, and pepsin+trypsin+chymotrypsin. Peptides released from the collagens having comparable A_E and W were estimated for their likelihood to be bioactive using PeptideRanker Score. The collagens test

SUBMITTER: Iwaniak A 

PROVIDER: S-EPMC7404701 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature