The association between markers of liver injury and clinical outcomes in patients with COVID-19 in Wuhan.

ABSTRACT:

Background

The outbreak of coronavirus disease 2019 (COVID-19) is a critical challenge for public health. The effect of COVID-19 on liver injury has not been fully established.

Aims

To evaluate the dynamic changes in liver function and the relationship between liver damage and prognosis in patients with COVID-19.

Methods

Retrospective analysis of clinical data of 675 patients with COVID-19 in Zhongnan Hospital of Wuhan University from January 3 to March 8, 2020. Patients were classified as having normal or abnormal liver function and liver injury.

Results

Of 675 patients, 253 (37.5%) had abnormal liver function during hospitalisation, and 52 (7.7%) had liver injury. The dynamic changes of ALT and AST levels were more significant in patients with liver injury an

SUBMITTER: Huang H 

PROVIDER: S-EPMC7404742 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature