Early Puberty and Telomere Length in Preadolescent Girls and Mothers.

ABSTRACT:

Objective

To test the association between early puberty and telomere length in preadolescent girls and mothers from a large representative sample of US females.

Study design

We analyzed data from 1194 preadolescent girls and 2421 mothers from the Fragile Families and Child Wellbeing Study. Participants were from a population-based birth cohort (1998-2000) born in large US cities. Telomere length was assessed by quantitative polymerase chain reaction from saliva samples provided by preadolescent girls and mothers of preadolescent youth. Mothers completed a questionnaire about their child's pubertal development to determine concurrent Tanner stages and provided self-reports of her own age at menarche. Linear regression models were used to estimate the association between puber

SUBMITTER: Koss KJ 

PROVIDER: S-EPMC7405936 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature