Testicular volume and clinical correlates of hypothalamic-pituitary-testicular function: A cross-sectional study in obese men.

ABSTRACT: The aim of this study was to determine whether testicular volume is correlated with clinical and biochemical markers of hypothalamic-pituitary-testicular (HPT) axis function. This was a cross-sectional substudy of a larger randomized controlled trial including obese men, body mass index (BMI) ≥30 kg m^-2, with a total testosterone level <12 nmol l^-1. Testicular volume was measured by orchidometer, testosterone by liquid chromatography/tandem mass spectrometry, and body composition by dual-energy X-ray absorptiometry. Men completed the Aging Males' Symptoms (AMS) score, International Index of Erectile Function-5 (IIEF-5), physical function, and handgrip dynamometer testing. Eighty-nine men participated with a median (interquartile range [IQR]) age of 53.1 (47.6, 59.2) y

SUBMITTER: Tang Fui MN 

PROVIDER: S-EPMC7406092 | biostudies-literature | 2020 Jul-Aug

REPOSITORIES: biostudies-literature