Immune response to SARS-CoV-2 in health care workers following a COVID-19 outbreak: A prospective longitudinal study.

ABSTRACT:

Objective

Currently, little is known about the progression of an immune response against SARSCoV- 2 upon infection or sub-infection-exposure over time. We examined the serologic response in healthcare workers up to 12 weeks after a well-documented and contained outbreak and compared results with findings from earlier serologic testing in the same population.

Methods

This study followed 166 health care workers of the University Perinatal Care Center, Regensburg, Germany, for up to 12 weeks. 27 of the subjects had previously tested positive for the presence of SARS-CoV-2 by PCR testing and developed COVID-19. Serologic responses were tested with two independent commercially available test kits.

Results

77.8 % of COVID-19 study subjects developed a specific IgG-response

SUBMITTER: Fill Malfertheiner S 

PROVIDER: S-EPMC7406471 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature