Electroconvulsive therapy modulates functional interactions between submodules of the emotion regulation network in major depressive disorder.

ABSTRACT: An increasing number of neuroimaging studies have consistently revealed that disrupted functional interactions within the cognitive emotion regulation network (ERN) contribute to the onset of major depressive disorders (MDD). To disentangle the functional reorganization of ERN after electroconvulsive therapy (ECT) in MDD is curial for understanding its neuropathology. Resting-state functional magnetic resonance imaging data was collected from 23 MDD patients before and after ECT, as well as 25 healthy controls. Network modularity analysis was used to identify the submodules and functional connectivity (FC) was used to investigate the functional reorganization of ERN in the MDD patients after ECT. Four submodules of ERN were identified, including emotion response module (ERM), emotion integ

SUBMITTER: Xu J 

PROVIDER: S-EPMC7406501 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature