A First Insight into North American Plant Pathogenic Fungi Armillaria Sinapina Transcriptome.

ABSTRACT: Armillaria sinapina, a fungal pathogen of primary timber species of North American forests, causes white root rot disease that ultimately kills the trees. A more detailed understanding of the molecular mechanisms underlying this illness will support future developments on disease resistance and management, as well as in the decomposition of cellulosic material for further use. In this study, RNA-Seq technology was used to compare the transcriptome profiles of A. sinapina fungal culture grown in yeast malt broth medium supplemented or not with betulin, a natural compound of the terpenoid group found in abundance in white birch bark. This was done to identify enzyme transcripts involved in the metabolism (redox reaction) of betulin into betulinic acid, a potent anticancer drug. De novo assem

SUBMITTER: Fradj N 

PROVIDER: S-EPMC7407180 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature