Concentrations of Essential Trace Metals in the Brain of Animal Species-A Comparative Study.

ABSTRACT: The essential trace metals iron, zinc, and copper have a significant physiological role in healthy brain development and function. Especially zinc is important for neurogenesis, synaptogenesis, synaptic transmission and plasticity, and neurite outgrowth. Given the key role of trace metals in many cellular processes, it is important to maintain adequate levels in the brain. However, the physiological concentration of trace metals, and in particular zinc, in the human and animal brain is not well described so far. For example, little is known about the trace metal content of the brain of animals outside the class of mammals. Here, we report the concentration of iron, zinc, and copper in fresh brain tissue of different model-species of the phyla Chordata (vertebrates (mammals, fish)), Annelid

SUBMITTER: DeBenedictis CA 

PROVIDER: S-EPMC7407190 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature