Ontology highlight
ABSTRACT:
SUBMITTER: Sahinbegovic H
PROVIDER: S-EPMC7407231 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Cancers 20200704 7
Cell-to-cell communication is a fundamental process in every multicellular organism. In addition to membrane-bound and released factors, the sharing of cytosolic components represents a new, poorly explored signaling route. An extraordinary example of this communication channel is the direct transport of mitochondria between cells. In this review, we discuss how intercellular mitochondrial transfer can be used by cancer cells to sustain their high metabolic requirements and promote drug resistan ...[more]