Assessment and Treatment Outcomes of Persistent Radiation-Induced Alopecia in Patients With Cancer.

ABSTRACT:

Importance

Persistent radiation-induced alopecia (pRIA) and its management have not been systematically described.

Objective

To characterize pRIA in patients with primary central nervous system (CNS) tumors or head and neck sarcoma.

Design, setting, and participants

A retrospective cohort study of patients from January 1, 2011, to January 30, 2019, was conducted at 2 large tertiary care hospitals and comprehensive cancer centers. Seventy-one children and adults diagnosed with primary CNS tumors or head and neck sarcomas were evaluated for pRIA.

Main outcomes and measures

The clinical and trichoscopic features, scalp radiation dose-response relationship, and response to topical minoxidil were assessed using standardized clinical photographs of the scalp, trichos

SUBMITTER: Phillips GS 

PROVIDER: S-EPMC7407362 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature