Long Noncoding RNAs and Circular RNAs in Autoimmune Diseases.

ABSTRACT: Immune responses are essential for the clearance of pathogens and the repair of injured tissues; however, if these responses are not properly controlled, autoimmune diseases can occur. Autoimmune diseases (ADs) are a family of disorders characterized by the body's immune response being directed against its own tissues, with consequent chronic inflammation and tissue damage. Despite enormous efforts to identify new drug targets and develop new therapies to prevent and ameliorate AD symptoms, no definitive solutions are available today. Additionally, while substantial progress has been made in drug development for some ADs, most treatments only ameliorate symptoms and, in general, ADs are still incurable. Hundreds of genetic loci have been identified and associated with ADs by genome-wide as

SUBMITTER: Lodde V 

PROVIDER: S-EPMC7407480 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature