Clinical Characterization of the Frequent Exacerbator Phenotype in Asthma.

ABSTRACT: Asthma exacerbation is episodic worsening of respiratory symptoms in conjunction with the deterioration of lung function, which may occur independently from the asthma severity hampering asthmatics' quality of life. This study aimed to characterize the patient phenotype more prone to asthma exacerbation (oral corticosteroid burst ≥2 per year) to allow the proper identification of such patients. This real-life, observational, cross-sectional study evaluated 464 asthmatic patients stratified according to the asthma exacerbations experienced in the previous year. Clinical, functional, and blood parameters were retrieved from chart data and were representative of patients in stable conditions. The frequent asthma exacerbator was more commonly female, suffered from chronic rhinosinusitis with n

SUBMITTER: Sprio AE 

PROVIDER: S-EPMC7408982 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature