The Salmonella enterica Plasmidome as a Reservoir of Antibiotic Resistance.

ABSTRACT: The emergence of multidrug-resistant bacterial strains worldwide has become a serious problem for public health over recent decades. The increase in antimicrobial resistance has been expanding via plasmids as mobile genetic elements encoding antimicrobial resistance (AMR) genes that are transferred vertically and horizontally. This study focuses on Salmonella enterica, one of the leading foodborne pathogens in industrialized countries. S. enterica is known to carry several plasmids involved not only in virulence but also in AMR. In the current paper, we present an integrated strategy to detect plasmid scaffolds in whole genome sequencing (WGS) assemblies. We developed a two-step procedure to predict plasmids based on i) the presence of essential elements for plasmid replication and

SUBMITTER: Emond-Rheault JG 

PROVIDER: S-EPMC7409225 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature