Characterization of Salmonella Phage LPST153 That Effectively Targets Most Prevalent Salmonella Serovars.

ABSTRACT: Foodborne diseases represent a major risk to public health worldwide. In this study, LPST153, a novel Salmonella lytic phage with halo (indicative of potential depolymerase activity) was isolated by employing Salmonella enterica serovar Typhimurium ATCC 13311 as the host and had excellent lytic potential against Salmonella. LPST153 is effectively able to lyse most prevalent tested serotypes of Salmonella, including S. Typhimurium, S. Enteritidis, S. Pullorum and S. Gallinarum. Morphological analysis revealed that phage LPST153 belongs to Podoviridae family and Caudovirales order and could completely prevent host bacterial growth within 9 h at multiplicity of infection (MOI) of 0.1, 1, 10 and 100. LPST153 had a latent per

SUBMITTER: Islam MS 

PROVIDER: S-EPMC7409278 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature