Population Analysis and Evolution of Saccharomyces cerevisiae Mitogenomes.

ABSTRACT: The study of mitogenomes allows the unraveling of some paths of yeast evolution that are often not exposed when analyzing the nuclear genome. Although both nuclear and mitochondrial genomes are known to determine phenotypic diversity and fitness, no concordance has yet established between the two, mainly regarding strains' technological uses and/or geographical distribution. In the current work, we proposed a new method to align and analyze yeast mitogenomes, overcoming current difficulties that make it impossible to obtain comparable mitogenomes for a large number of isolates. To this end, 12,016 mitogenomes were considered, and we developed a novel approach consisting of the design of a reference sequence intended to be comparable between all mitogenomes. Subsequently, the population str

SUBMITTER: Vieira D 

PROVIDER: S-EPMC7409325 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature