The correlation of intraoperative hypotension and postoperative cognitive impairment: a meta-analysis of randomized controlled trials.

ABSTRACT:

Background

There is no consensus on whether intraoperative hypotension is associated with postoperative cognitive impairment. Hence, we performed a meta-analysis to evaluate the correlation of intraoperative hypotension and the incidence of postoperative delirium (POD) or postoperative cognitive dysfunction (POCD).

Methods

We searched PubMed, Embase, and Cochrane Library databases to find randomized controlled trials (RCTs) in which reported the relationship between intraoperative hypotension and POD or POCD. The retrieval time is up to January 2020, without language restrictions. Quality assessment of the eligible studies was conducted by two researchers independently with the Cochrane evaluation system.

Results

We analyzed five eligible RCTs. Based on the relative m

SUBMITTER: Feng X 

PROVIDER: S-EPMC7409718 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature